Yup
I have all my kids and grandkids along with Grandpa's & my sun, moon, acending, and decending signs in a book. I should go back and find where their Venus and Mars set too. But I can look at each one and find out why and how we mesh the way we do.
Our son has Cap & Cancer that his dad and I are. He gets along with everyone or can do it smoothly till he gets away from us.
His moon meshes with his older sisters ascending sign. They can live together, but with friction.
Their younger sister has only one sign that gets along with one of theirs.
All the signs of our grandkids all get along with something in all of the adult signs. Now my oldest grandson and I have the same moon sign.
He is a charmer and we can get along real good. Our moon signs are Libra.
I think it matters.
Barb