I actually have kind of been "commissioned" to read with my Minchiate (an il Meneghello one; whichever is the less sought-after, I am forgetting the name!).
My own overall card-reading system is pretty intuitive already. I very much read the images and how they interact in a spread, in context with the question being asked. I also am heavily into astrology so that does help with that portion of the deck. The elements and other specialties I just take as they come.
In short, I have a very open style of reading that lends itself well to most any deck, and I find the Minchiate no exception. In fact, I find that it gives me a lot of similar information that any tarot deck would give--it just spreads that information out a little farther rather than clustering lots of things together. A "clustery" deck would be in the RWS vein, in my eyes: a deck that jams a lot of specifics in visually.
Etteillas are the most difficult in my eyes, but I find them a really nice challenge because they are very, very systematic and different.
Does this make sense? Doesn't seem like I have much of a "system" at all, but I hope I've helped!