There is little on eclipses opposite/on the node, I've been thtrough this search myself. If it signifies something.. I've had an eclipse conjunct my NN already. I can certainly tell that certain beginnings were either taking place at this point or being planned with clear intention, therefore life changed or was about to change. However, I have to say that at the time I was in a New Moon solar return AND a progressive New Moon period (which of course sets the tone for many years to come), a rare coincidence. As with any astrological aspect in transits, in my opinion, few of them will deliver real life event if not supported somehow - solar, progressions, directions (with some exceptions like Saturn who, in my opinion, always delivers, Jupiter often does, Mars too, depending on the personal chart).
In short, I don't think the eclipse itself would have been enough and because of my New Moon aspects I can't say that the eclipse set the beginning of a new period in my life BUT I do think it helped.