I hear that Saturn is most comfortable
Saturn actually 'joys' in the Twelfth - it's a diurnal or day planet. So the sixth happens to be the house opposite it's Joy. It's always difficult to give one or two key words for planets as they are all multi-faceted but you might see Saturn's 'instinctive' response being to deny, exclude, reject, constrain, delay. However what is 'instinctive' isn't always what you get. Saturn can well grudgingly allow and indeed encourage, especially when it is dignified in the chart, as yours is. Ronia's list of her experience of Saturn shows that - you have to work hard to get what Saturn signifies but it can be done.
Judging the extent to which it can be done depends on the condition of Saturn, by sign, house and aspect. Even hard aspects to Saturn from Jupiter can actually provide impetus and encouragement, Mars principle of being incisive (literally) can stop delays and promote action. Again it will depend where Jupiter and Mars are in the chart and their condition.
The sixth covers a number of areas of life. They tend not to be the ones of day to day importance (though for some they can be). Disease is one, and you might be prone to Saturnian problems, relating to teeth, knees, bones, or at a mental level, depression. I have Saturn conjunct my Ascendant, which shows the physical body, as well as mind, and spirit. I have therefore issues with all of those, except depression, but they have not yet translated as recurring diseases.
Pets and small animals is another area, employees, members of a team you run trades people you use are other significations, as is your children's money (when and if you have children). The hard aspects you mention relate Saturn's influence to other houses, which could be the twelfth if an opposition is involved or ninth or third if squares are involved - assuming no issues with interception. If one or more of those aspects is out of sign, then you should downgrade it or even ignore it. Aspects have qualities that depend on their sign relationships, they're not just geometric angles (unless you discard the Zodiac entirely).